The result of the NIPT

There is no evidence of any chromosomal abnormality

About 993 in 1000 pregnant people get this result. It is almost always accurate. It is very unlikely that you are carrying a child with a chromosomal abnormality. Fewer than 1 in 1000 pregnant people are carrying a child with a chromosomal abnormality. Follow-up testing is not needed.

There is evidence of a chromosomal abnormality

About 7 in 1000 pregnant people get this result. You may be carrying a child with a chromosomal abnormality. There are two options:

1. There is evidence of Down syndrome, Edwards syndrome or Patau syndrome. You will be called by your midwife. Your midwife will tell you which of the three conditions your child may have.
2. There is evidence of some other chromosomal abnormality. Your midwife will call you to schedule a video call with your midwife and a doctor (clinical geneticist) from Amsterdam UMC. During the video call, you hear what has been found and what this could mean for your child or yourself. You can also ask questions.

You can choose to have follow-up testing to be sure.

The test did not work

In about 20 out of 1,000 women, the NIPT does not work and no results are obtained. There could be various reasons for this. If the NIPT did not work in your case, you can have the test done again. This requires another blood sample to be taken. About 4 in 5 pregnant people will have a successful NIPT the second time.

Sometimes the NIPT does not work the second time either

There could be various reasons for this. The reason will be stated in a letter with the result.  Usually, it is because there is too little genetic material (DNA) from the placenta in the mother’s blood. This DNA is almost always the same as that of the child, and that is checked in the NIPT. If the NIPT did not work the second time, you can have the NIPT done again.